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Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin
Uncoupling protein 1 (UCP1) catalyzes fatty acid-activated, purine nucleotide-sensitive proton leak across the mitochondrial inner membrane of brown adipose tissue to produce heat, and could help combat obesity and metabolic disease in humans. Studies over the last 30 years conclude that the protein...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460439/ https://ncbi.nlm.nih.gov/pubmed/26038550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503833112 |
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