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The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism

Uncoupling protein 1 (UCP1) is an integral membrane protein found in the mitochondrial inner membrane of brown adipose tissue, and facilitates the process of non-shivering thermogenesis in mammals. Its activation by fatty acids, which overcomes its inhibition by purine nucleotides, leads to an incre...

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Detalhes bibliográficos
Publicado no:Biochimie
Main Authors: Crichton, Paul G., Lee, Yang, Kunji, Edmund R.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395090/
https://ncbi.nlm.nih.gov/pubmed/28057583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2016.12.016
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