Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity

Biophysical investigation of membrane proteins generally requires their extraction from native sources using detergents, a step that can lead, possibly irreversibly, to protein denaturation. The propensity of dodecylphosphocholine (DPC), a detergent widely utilized in NMR studies of membrane protein...

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Udgivet i:Biophys J
Main Authors: Dehez, François, Schanda, Paul, King, Martin S., Kunji, Edmund R.S., Chipot, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2017
Fag:
Biophysical Letters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722206/
https://ncbi.nlm.nih.gov/pubmed/29056231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.09.019
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