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High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

[Image: see text] Actinobacteria, particularly those of genus Streptomyces, remain invaluable hosts for the discovery and engineering of natural products and their cognate biosynthetic pathways. However, genetic manipulation of these bacteria is often labor and time intensive. Here, we present an en...

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Detaylı Bibliyografya
Yayımlandı:ACS Synth Biol
Asıl Yazarlar: Cobb, Ryan E., Wang, Yajie, Zhao, Huimin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459934/
https://ncbi.nlm.nih.gov/pubmed/25458909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb500351f
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