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ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
Therapy resistance is a major clinical problem in cancer medicine and crucial for disease relapse and progression. Therefore, the clinical need to overcome it, particularly for aggressive tumors such as pancreatic cancer, is very high. Aberrant activation of an epithelial–mesenchymal transition (EMT...
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| Publicat a: | EMBO Mol Med |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BlackWell Publishing Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459821/ https://ncbi.nlm.nih.gov/pubmed/25872941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404396 |
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