Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.

Lignende værker

• Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers
  af: Yuedi Ding, et al.
  Udgivet: (2020-06-01)
• Antitumor efficacy of cytosine deaminase-armed vaccinia virus plus 5-fluorocytosine in colorectal cancers
  af: Ding, Yuedi, et al.
  Udgivet: (2020)
• Interaction of endothelial progenitor cells expressing cytosine deaminase in tumor tissues and 5‐fluorocytosine administration suppresses growth of 5‐fluorouracil‐sensitive liver cancer in mice
  af: Torimura, Takuji, et al.
  Udgivet: (2012)
• Yeast Cytosine Deaminase Mutants with Increased Thermostability Impart Sensitivity to 5-Fluorocytosine
  af: Stolworthy, Tiffany S., et al.
  Udgivet: (2008)
• Role of Glutamate 64 in the Activation of the Prodrug 5-fluorocytosine by Yeast Cytosine Deaminase
  af: Wang, Jifeng, et al.
  Udgivet: (2011)