A novel CGRP-neutralizing Spiegelmer attenuates neurogenic plasma protein extravasation

BACKGROUND AND PURPOSE: Calcitonin gene-related peptide (CGRP) plays an important role in the pathology of migraine, and recent clinical trials suggest the inhibition of CGRP-mediated processes as a new therapeutic option in migraine. In this study, we describe the generation of NOX-L41, a CGRP-neut...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Hoehlig, K, Johnson, K W, Pryazhnikov, E, Maasch, C, Clemens-Smith, A, Purschke, W G, Vauléon, S, Buchner, K, Jarosch, F, Khiroug, L, Vater, A, Klussmann, S
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459025/
https://ncbi.nlm.nih.gov/pubmed/25659966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13110
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