A Phosphoproteomic Comparison of B-RAF(V600E) and MKK1/2 Inhibitors in Melanoma Cells

Inhibitors of oncogenic B-RAF(V600E) and MKK1/2 have yielded remarkable responses in B-RAF(V600E)-positive melanoma patients. However, the efficacy of these inhibitors is limited by the inevitable onset of resistance. Despite the fact that these inhibitors target the same pathway, combination treatm...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: Stuart, Scott A., Houel, Stephane, Lee, Thomas, Wang, Nan, Old, William M., Ahn, Natalie G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458723/
https://ncbi.nlm.nih.gov/pubmed/25850435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.047233
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars