RNA Interference Screen to Identify Kinases That Suppress Rescue of ΔF508-CFTR

Cystic Fibrosis (CF) is an autosomal recessive disorder caused by mutations in the gene encoding the Cystic fibrosis transmembrane conductance regulator (CFTR). ΔF508-CFTR, the most common disease-causing CF mutant, exhibits folding and trafficking defects and is retained in the endoplasmic reticulu...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Trzcińska-Daneluti, Agata M., Chen, Anthony, Nguyen, Leo, Murchie, Ryan, Jiang, Chong, Moffat, Jason, Pelletier, Lawrence, Rotin, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458721/
https://ncbi.nlm.nih.gov/pubmed/25825526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.046375
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