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Circadian clock gene CRY2 degradation is involved in chemoresistance of colorectal cancer

Biomarkers for predicting chemotherapy response are important to treatment of colorectal cancer (CRC) patients. Cryptochrome 2 (CRY2) is a circadian clock protein involved in cell cycle, but the biological consequences of this activity in cancer are poorly understood. We set up biochemical and cell...

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Detalles Bibliográficos
Publicado en:Mol Cancer Ther
Main Authors: Fang, Lekun, Yang, Zihuan, Zhou, Junyi, Tung, Jung-Yu, Hsiao, Chwan-Deng, Wang, Lei, Deng, Yanhong, Wang, Puning, Wang, Jianping, Lee, Mong-Hong
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458447/
https://ncbi.nlm.nih.gov/pubmed/25855785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0030
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