Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: enhancement of cytotoxicity with epigenetic modulators

Clofarabine (Clo), fludarabine (Flu) and busulfan (Bu) combinations are efficacious in hematopoietic stem cell transplantation (HSCT) for myeloid leukemia. We now determined if the more affordable drug cladribine (Clad) can provide a viable alternative to Clo, with or without panobinostat (Pano) and...

Full description

Saved in:
Bibliographic Details
Published in:Exp Hematol
Main Authors: Valdez, Benigno C., Li, Yang, Murray, David, Ji, Jie, Liu, Yan, Popat, Uday, Champlin, Richard E., Andersson, Borje S.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458397/
https://ncbi.nlm.nih.gov/pubmed/25704054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.02.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items