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Enema ion compositions for enhancing colorectal drug delivery

Delivering drugs to the colorectum by enema has advantages for treating or preventing both local and systemic diseases. However, the properties of the enema itself are not typically exploited for improving drug delivery. Sodium ions are actively pumped out of the lumen of the colon, which is followe...

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Опубликовано в: :J Control Release
Главные авторы: Maisel, Katharina, Chattopadhyay, Sumon, Moench, Thomas, Hendrix, Craig, Cone, Richard, Ensign, Laura M., Hanes, Justin
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458383/
https://ncbi.nlm.nih.gov/pubmed/25937321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.04.040
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