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Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake
Mucosal epithelia use osmotic gradients for fluid absorption and secretion. We hypothesized that administration of hypotonic solutions would induce fluid uptake that could be advantageous for rapidly delivering drugs through mucus to the vaginal epithelium. We found that hypotonic formulations marke...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767980/ https://ncbi.nlm.nih.gov/pubmed/23769419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.039 |
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