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Enema ion compositions for enhancing colorectal drug delivery

Delivering drugs to the colorectum by enema has advantages for treating or preventing both local and systemic diseases. However, the properties of the enema itself are not typically exploited for improving drug delivery. Sodium ions are actively pumped out of the lumen of the colon, which is followe...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Maisel, Katharina, Chattopadhyay, Sumon, Moench, Thomas, Hendrix, Craig, Cone, Richard, Ensign, Laura M., Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458383/
https://ncbi.nlm.nih.gov/pubmed/25937321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.04.040
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