Febuxostat improves outcome in a rat model of cancer cachexia

BACKGROUND: Activity of xanthine oxidase is induced in cancer cachexia, and its inhibition by allopurinol or oxypurinol improves survival and reduces wasting in the Yoshida hepatoma cancer cachexia model. Here, we tested the effects of the second-generation xanthine oxidase inhibitor febuxostat comp...

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Detaylı Bibliyografya
Yayımlandı:J Cachexia Sarcopenia Muscle
Asıl Yazarlar: Konishi, Masaaki, Pelgrim, Loes, Tschirner, Anika, Baumgarten, Anna, von Haehling, Stephan, Palus, Sandra, Doehner, Wolfram, Anker, Stefan D, Springer, Jochen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458083/
https://ncbi.nlm.nih.gov/pubmed/26136193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12017
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