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IGF-1 treatment reduces weight loss and improves outcome in a rat model of cancer cachexia
BACKGROUND: A hallmark symptom of cancer cachexia is the loss of skeletal muscle. This is at least partially due to a deregulation of the growth hormone/IGF-1 axis and a subsequently impaired protein synthesis in skeletal muscle. Here, we investigated the effect of IGF-1 supplementation in a rat mod...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117996/ https://ncbi.nlm.nih.gov/pubmed/21766056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-011-0029-3 |
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