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Febuxostat improves outcome in a rat model of cancer cachexia
BACKGROUND: Activity of xanthine oxidase is induced in cancer cachexia, and its inhibition by allopurinol or oxypurinol improves survival and reduces wasting in the Yoshida hepatoma cancer cachexia model. Here, we tested the effects of the second-generation xanthine oxidase inhibitor febuxostat comp...
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| 出版年: | J Cachexia Sarcopenia Muscle |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458083/ https://ncbi.nlm.nih.gov/pubmed/26136193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12017 |
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