A Novel Osteogenic Oxysterol Compound for Therapeutic Development to Promote Bone Growth: Activation of Hedgehog Signaling and Osteogenesis through Smoothened Binding

Osteogenic factors are often used in orthopedics to promote bone growth, improve fracture healing, and induce spine fusion. Osteogenic oxysterols are naturally occurring molecules that were shown to induce osteogenic differentiation in vitro and promote spine fusion in vivo. The purpose of this stud...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Montgomery, Scott R., Nargizyan, Taya, Meliton, Vicente, Nachtergaele, Sigrid, Rohatgi, Rajat, Stappenbeck, Frank, Jung, Michael E., Johnson, Jared S., Aghdasi, Bayan, Tian, Haijun, Weintraub, Gil, Inoue, Hirokazu, Atti, Elisa, Tetradis, Sotirios, Pereira, Renata C, Hokugo, Akishige, Alobaidaan, Raed, Tan, Yanlin, Hahn, Theodor J., Wang, Jeffrey C, Parhami, Farhad
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457783/
https://ncbi.nlm.nih.gov/pubmed/24591126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2213
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados