A Novel Osteogenic Oxysterol Compound for Therapeutic Development to Promote Bone Growth: Activation of Hedgehog Signaling and Osteogenesis through Smoothened Binding

Osteogenic factors are often used in orthopedics to promote bone growth, improve fracture healing, and induce spine fusion. Osteogenic oxysterols are naturally occurring molecules that were shown to induce osteogenic differentiation in vitro and promote spine fusion in vivo. The purpose of this stud...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Bone Miner Res
Hlavní autoři: Montgomery, Scott R., Nargizyan, Taya, Meliton, Vicente, Nachtergaele, Sigrid, Rohatgi, Rajat, Stappenbeck, Frank, Jung, Michael E., Johnson, Jared S., Aghdasi, Bayan, Tian, Haijun, Weintraub, Gil, Inoue, Hirokazu, Atti, Elisa, Tetradis, Sotirios, Pereira, Renata C, Hokugo, Akishige, Alobaidaan, Raed, Tan, Yanlin, Hahn, Theodor J., Wang, Jeffrey C, Parhami, Farhad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457783/
https://ncbi.nlm.nih.gov/pubmed/24591126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2213
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky