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Targeting Cdc20 as a novel cancer therapeutic strategy
The Anaphase Promoting Complex (APC, also called APC/C) regulates cell cycle progression by forming two closely related, but functionally distinct E3 ubiquitin ligase sub-complexes, APC(Cdc20) and APC(Cdh1), respectively. Emerging evidence has begun to reveal that Cdc20 and Cdh1 have opposing functi...
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| Publicado en: | Pharmacol Ther |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457591/ https://ncbi.nlm.nih.gov/pubmed/25850036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.04.002 |
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