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Drug screening strategy for human membrane proteins: from NMR protein backbone structure to in silica- and NMR-screened hits
About 8,000 genes encode membrane proteins in the human genome. The information about their druggability will be very useful to facilitate drug discovery and development. The main problem, however, consists of limited structural and functional information about these proteins because they are diffic...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457379/ https://ncbi.nlm.nih.gov/pubmed/24525125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.01.179 |
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