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Detergent/Nanodisc Screening for High-Resolution NMR Studies of an Integral Membrane Protein Containing a Cytoplasmic Domain

Because membrane proteins need to be extracted from their natural environment and reconstituted in artificial milieus for the 3D structure determination by X-ray crystallography or NMR, the search for membrane mimetic that conserve the native structure and functional activities remains challenging....

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Detalhes bibliográficos
Main Authors: Tzitzilonis, Christos, Eichmann, Cédric, Maslennikov, Innokentiy, Choe, Senyon, Riek, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551814/
https://ncbi.nlm.nih.gov/pubmed/23349867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054378
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