Facile backbone structure determination of human membrane proteins by NMR spectroscopy

Although nearly half of today’s major pharmaceutical drugs target human integral membrane proteins (hIMPs), only 30 hIMP structures are currently available in the Protein Data Bank, largely owing to inefficiencies in protein production. Here we describe a strategy for the rapid structure determinati...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Klammt, Christian, Maslennikov, Innokentiy, Bayrhuber, Monika, Eichmann, Cédric, Vajpai, Navratna, Chiu, Ellis Jeremy Chua, Blain, Katherine Y, Esquivies, Luis, Kwon, June Hyun Jung, Balana, Bartosz, Pieper, Ursula, Sali, Andrej, Slesinger, Paul A, Kwiatkowski, Witek, Riek, Roland, Choe, Senyon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723349/
https://ncbi.nlm.nih.gov/pubmed/22609626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2033
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge