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Large expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells
Trinucleotide repeat expansion disorders (TRED) are caused by genomic expansions of trinucleotide repeats, such as CTG and CAG. These expanded repeats are unstable in germline and somatic cells, with potential consequences for disease severity. Previous studies have demonstrated the involvement of D...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457148/ https://ncbi.nlm.nih.gov/pubmed/26047474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11020 |
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