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Bidirectional transcription stimulates expansion and contraction of expanded (CTG)•(CAG) repeats
More than 12 neurogenetic disorders are caused by unstable expansions of (CTG)•(CAG) repeats. The expanded repeats are unstable in germline and somatic cells, with potential consequences for disease severity. Previous studies have shown that contractions of (CAG)(95) are more frequent when the repea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3016912/ https://ncbi.nlm.nih.gov/pubmed/21088112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq501 |
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