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Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

Cost-effective animal models that accurately reflect the pathological progression of pulmonary tuberculosis are needed to screen and evaluate novel tuberculosis drugs and drug regimens. Pulmonary disease in humans is characterized by a number of heterogeneous lesion types that reflect differences in...

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書誌詳細
出版年:Dis Model Mech
主要な著者: Irwin, Scott M., Driver, Emily, Lyon, Edward, Schrupp, Christopher, Ryan, Gavin, Gonzalez-Juarrero, Mercedes, Basaraba, Randall J., Nuermberger, Eric L., Lenaerts, Anne J.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457037/
https://ncbi.nlm.nih.gov/pubmed/26035867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019570
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