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Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis
Mice are the most commonly used species for non-clinical evaluations of drug efficacy against tuberculosis (TB). Unlike commonly used strains, C3HeB/FeJ mice develop caseous necrosis in the lung, which might alter the representation of drug efficacy in a way that is more like human TB. Because the d...
Uloženo v:
| Vydáno v: | Dis Model Mech |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457036/ https://ncbi.nlm.nih.gov/pubmed/26035868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019513 |
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