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The p53 Target Gene Siva Enables Non-Small Cell Lung Cancer Development

Although p53 transcriptional activation potential is critical for its ability to suppress cancer, the specific target genes involved in tumor suppression remain unclear. Siva is a p53 target gene essential for p53-dependent apoptosis, although it can also promote proliferation through inhibition of...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Van Nostrand, Jeanine L., Brisac, Alice, Mello, Stephano S., Jacobs, Suzanne B. R., Luong, Richard, Attardi, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456277/
https://ncbi.nlm.nih.gov/pubmed/25813352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0921
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