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Molecular mechanism of resolving trinucleotide repeat hairpin by helicases
Trinucleotide repeat (TNR) expansion is the root cause for many known congenital neurological and muscular disorders in human including Huntington's disease, Fragile X syndrome and Friedreich's ataxia. The stable secondary hairpin structures formed by TNR may trigger fork stalling during r...
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| Vydáno v: | Structure |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456222/ https://ncbi.nlm.nih.gov/pubmed/26004439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.006 |
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