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Mechanistic Studies of Hairpin to Duplex Conversion for Trinucleotide Repeat Sequences

The expansion of a trinucleotide repeat sequence, such as CAG/CTG, has been pinpointed as the molecular basis for a number of neurodegenerative disorders. It has been proposed that as part of the expansion process, these repetitive sequences adopt non-B conformations such as hairpins. However, the p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ávila Figueroa, Amalia, Delaney, Sarah
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863172/
https://ncbi.nlm.nih.gov/pubmed/20228068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061853
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