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Mechanistic Studies of Hairpin to Duplex Conversion for Trinucleotide Repeat Sequences
The expansion of a trinucleotide repeat sequence, such as CAG/CTG, has been pinpointed as the molecular basis for a number of neurodegenerative disorders. It has been proposed that as part of the expansion process, these repetitive sequences adopt non-B conformations such as hairpins. However, the p...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863172/ https://ncbi.nlm.nih.gov/pubmed/20228068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061853 |
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