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A Small Unstructured Nucleic Acid Disrupts a Trinucleotide Repeat Hairpin

A variety of neurodegenerative disorders are associated with the expansion of trinucleotide repeat (TNR) sequences. These repetitive sequences are prone to adopting non-canonical structures, such as intrastrand stem-loop hairpins. Indeed, the formation and persistence of these hairpins during DNA re...

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Autors principals: Ávila-Figueroa, Amalia, Cattie, Douglas, Delaney, Sarah
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190016/
https://ncbi.nlm.nih.gov/pubmed/21924238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.130
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