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A Small Unstructured Nucleic Acid Disrupts a Trinucleotide Repeat Hairpin
A variety of neurodegenerative disorders are associated with the expansion of trinucleotide repeat (TNR) sequences. These repetitive sequences are prone to adopting non-canonical structures, such as intrastrand stem-loop hairpins. Indeed, the formation and persistence of these hairpins during DNA re...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190016/ https://ncbi.nlm.nih.gov/pubmed/21924238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.130 |
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