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On the lack of polymorphism in Aβ-peptide aggregates derived from patient brains

The amyloid beta (Aβ) oligomers and fibrils that are found in neural tissues of patients suffering from Alzheimer's disease may either cause or contribute to the pathology of the disease. In vitro, these Aβ-aggregates are characterized by structural polymorphism. However, recent solid state NMR...

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書目詳細資料
發表在:Protein Sci
Main Authors: Alred, Erik J, Phillips, Malachi, Berhanu, Workalemahu M, Hansmann, Ulrich H E
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456106/
https://ncbi.nlm.nih.gov/pubmed/25739352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2668
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