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IL-4 upregulates Igα and Igβ protein, resulting in augmented IgM maturation and BCR-triggered B cell activation()
Interleukin 4 (IL-4) is critical for optimal B cell activation and germinal center B cell expansion in T-dependent immune responses; however, the underlying mechanism remains elusive. In the present study, we found that primary B cells express little Igα and Igβ protein despite substantial levels of...
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| Publicado no: | J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456092/ https://ncbi.nlm.nih.gov/pubmed/23776171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203211 |
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