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IL-4 rescues surface IgM expression in chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) cells express poor levels of surface immunoglobulin (sIg), and many are minimally activated or anergic in response to B-cell receptor (BCR) crosslinking in vitro. Paradoxically, CLL cells in patients are highly activated through BCR signaling and expand in prolifer...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4965907/ https://ncbi.nlm.nih.gov/pubmed/27226435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-682997 |
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