Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK

B-cell receptor (BCR) signaling plays a key role in the behavior of chronic lymphocytic leukemia (CLL). However, cellular consequences of signaling are incompletely defined. Here we explored possible links between BCR signaling and the unfolded protein response (UPR), a stress response pathway that...

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Vydáno v:Blood
Hlavní autoři: Krysov, Sergey, Steele, Andrew J., Coelho, Vania, Linley, Adam, Sanchez Hidalgo, Marina, Carter, Matthew, Potter, Kathleen N., Kennedy, Benjamin, Duncombe, Andrew S., Ashton-Key, Margaret, Forconi, Francesco, Stevenson, Freda K., Packham, Graham
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231419/
https://ncbi.nlm.nih.gov/pubmed/25170122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567198
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