Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK

B-cell receptor (BCR) signaling plays a key role in the behavior of chronic lymphocytic leukemia (CLL). However, cellular consequences of signaling are incompletely defined. Here we explored possible links between BCR signaling and the unfolded protein response (UPR), a stress response pathway that...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Krysov, Sergey, Steele, Andrew J., Coelho, Vania, Linley, Adam, Sanchez Hidalgo, Marina, Carter, Matthew, Potter, Kathleen N., Kennedy, Benjamin, Duncombe, Andrew S., Ashton-Key, Margaret, Forconi, Francesco, Stevenson, Freda K., Packham, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231419/
https://ncbi.nlm.nih.gov/pubmed/25170122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567198
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