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The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy

Biologists and clinicians agree that the B-cell receptor influences the behavior of chronic lymphocytic leukemia, and promising new drugs are aimed at receptor-associated kinases. Engagement of surface immunoglobulin by antigen is a key driver of malignant cells with outcome influenced by the nature...

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Detalhes bibliográficos
Main Authors: Packham, Graham, Krysov, Serge, Allen, Alex, Savelyeva, Natalia, Steele, Andrew J., Forconi, Francesco, Stevenson, Freda K.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077074/
https://ncbi.nlm.nih.gov/pubmed/24986876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.098384
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