Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease

Increasing evidence has shown the aberrant expression of inflammasome-related proteins in Alzheimer's disease (AD) brain; these proteins, including NLRP1 inflammasome, are implicated in the execution of inflammatory response and pyroptotic death. Although current data are associated NLRP1 genet...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Tan, M-S, Tan, L, Jiang, T, Zhu, X-C, Wang, H-F, Jia, C-D, Yu, J-T
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454321/
https://ncbi.nlm.nih.gov/pubmed/25144717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.348
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