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New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis

The present study was designed to investigate the role of β‐amyloid (Aβ(1‐42)) in inducing neuronal pyroptosis and its mechanism. Mice cortical neurons (MCNs) were used in this study, LPS + Nigericin was used to induce pyroptosis in MCNs (positive control group), and Aβ(1‐42) was used to interfere w...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Han, Chenyang, Yang, Yi, Guan, Qiaobing, Zhang, Xiaoling, Shen, Heping, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Guo, Li, Jiao, Qingcai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348172/
https://ncbi.nlm.nih.gov/pubmed/32521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15439
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