New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis

The present study was designed to investigate the role of β‐amyloid (Aβ(1‐42)) in inducing neuronal pyroptosis and its mechanism. Mice cortical neurons (MCNs) were used in this study, LPS + Nigericin was used to induce pyroptosis in MCNs (positive control group), and Aβ(1‐42) was used to interfere w...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Han, Chenyang, Yang, Yi, Guan, Qiaobing, Zhang, Xiaoling, Shen, Heping, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Guo, Li, Jiao, Qingcai
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348172/
https://ncbi.nlm.nih.gov/pubmed/32521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15439
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