New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis

The present study was designed to investigate the role of β‐amyloid (Aβ(1‐42)) in inducing neuronal pyroptosis and its mechanism. Mice cortical neurons (MCNs) were used in this study, LPS + Nigericin was used to induce pyroptosis in MCNs (positive control group), and Aβ(1‐42) was used to interfere w...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Han, Chenyang, Yang, Yi, Guan, Qiaobing, Zhang, Xiaoling, Shen, Heping, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Guo, Li, Jiao, Qingcai
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348172/
https://ncbi.nlm.nih.gov/pubmed/32521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15439
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