New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis

The present study was designed to investigate the role of β‐amyloid (Aβ(1‐42)) in inducing neuronal pyroptosis and its mechanism. Mice cortical neurons (MCNs) were used in this study, LPS + Nigericin was used to induce pyroptosis in MCNs (positive control group), and Aβ(1‐42) was used to interfere w...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Han, Chenyang, Yang, Yi, Guan, Qiaobing, Zhang, Xiaoling, Shen, Heping, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Guo, Li, Jiao, Qingcai
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348172/
https://ncbi.nlm.nih.gov/pubmed/32521573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15439
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