NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

BACKGROUND: Temporal lobe epilepsy (TLE) is often characterized pathologically by severe neuronal loss in the hippocampus. Understanding the mechanisms of neuron death is key to preventing the neurodegeneration associated with TLE. However, the involvement of neuronal loss to the epileptogenic proce...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Tan, Chen-Chen, Zhang, Jian-Guo, Tan, Meng-Shan, Chen, Hua, Meng, Da-Wei, Jiang, Teng, Meng, Xiang-Fei, Li, Ying, Sun, Zhen, Li, Meng-Meng, Yu, Jin-Tai, Tan, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314732/
https://ncbi.nlm.nih.gov/pubmed/25626361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0233-0
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