Inhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus

BACKGROUND: NLRP3 inflammasome is proposed to regulate inflammation in several neurological diseases, but its role in epilepsy remains largely unknown. This study aimed to investigate the role of the NLRP3 inflammasome in neuroinflammation, spontaneous recurrent seizures (SRS) and hippocampal neuron...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Meng, Xiang-Fei, Tan, Lan, Tan, Meng-Shan, Jiang, Teng, Tan, Chen-Chen, Li, Meng-Meng, Wang, Hui-Fu, Yu, Jin-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275944/
https://ncbi.nlm.nih.gov/pubmed/25516224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0212-5
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