NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

BACKGROUND: Temporal lobe epilepsy (TLE) is often characterized pathologically by severe neuronal loss in the hippocampus. Understanding the mechanisms of neuron death is key to preventing the neurodegeneration associated with TLE. However, the involvement of neuronal loss to the epileptogenic proce...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Tan, Chen-Chen, Zhang, Jian-Guo, Tan, Meng-Shan, Chen, Hua, Meng, Da-Wei, Jiang, Teng, Meng, Xiang-Fei, Li, Ying, Sun, Zhen, Li, Meng-Meng, Yu, Jin-Tai, Tan, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314732/
https://ncbi.nlm.nih.gov/pubmed/25626361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0233-0
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