An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina

Recent studies on the endoplasmic reticulum stress have shown that the unfolded protein response (UPR) is involved in the pathogenesis of inherited retinal degeneration caused by mutant rhodopsin. However, the main question of whether UPR activation actually triggers retinal degeneration remains to...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Rana, T, Shinde, V M, Starr, C R, Kruglov, A A, Boitet, E R, Kotla, P, Zolotukhin, S, Gross, A K, Gorbatyuk, M S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454166/
https://ncbi.nlm.nih.gov/pubmed/25522272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.539
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items