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Modulation of the rate of retinal degeneration in T17M RHO mice by reprogramming the Unfolded Protein Response
The goal of this study is to validate whether reprogramming of the UPR via modulation of pro-apoptotic caspase-7 and CHOP proteins could be an effective approach to slow down the rate of retinal degeneration in ADRP mice. In order to pursue our goal we created the T17M RHO CASP7 and T17M RHO CHOP mi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083741/ https://ncbi.nlm.nih.gov/pubmed/24664731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_58 |
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