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Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration
PURPOSE: The unfolded protein response is known to contribute to the inherited retinal pathology observed in T17M rhodopsin (T17M) mice. Recently it has been demonstrated that the endoplasmic reticulum stress–associated caspase-12 is activated during progression of retinal degeneration in different...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516015/ https://ncbi.nlm.nih.gov/pubmed/26207309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16924 |
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