An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina

Recent studies on the endoplasmic reticulum stress have shown that the unfolded protein response (UPR) is involved in the pathogenesis of inherited retinal degeneration caused by mutant rhodopsin. However, the main question of whether UPR activation actually triggers retinal degeneration remains to...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Rana, T, Shinde, V M, Starr, C R, Kruglov, A A, Boitet, E R, Kotla, P, Zolotukhin, S, Gross, A K, Gorbatyuk, M S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454166/
https://ncbi.nlm.nih.gov/pubmed/25522272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.539
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares