PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer

BACKGROUND: Tumour cells exclusively express the embryonic M2 isoform of pyruvate kinase (PKM2). PKM2 expression levels have been correlated with the effect of platinum compounds in cancer cell lines and xenograft models. The potential predictive role of PKM2 in patients with metastatic/advanced non...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Papadaki, C, Sfakianaki, M, Lagoudaki, E, Giagkas, G, Ioannidis, G, Trypaki, M, Tsakalaki, E, Voutsina, A, Koutsopoulos, A, Mavroudis, D, Georgoulias, V, Souglakos, J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453739/
https://ncbi.nlm.nih.gov/pubmed/25233397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.492
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares