Predictive Value of BRCA1, ERCC1, ATP7B, PKM2, TOPOI, TOPΟ-IIA, TOPOIIB and C-MYC Genes in Patients with Small Cell Lung Cancer (SCLC) Who Received First Line Therapy with Cisplatin and Etoposide

BACKGROUND: The aim of the study was to evaluate the predictive value of genes involved in the action of cisplatin-etoposide in Small Cell Lung Cancer (SCLC). METHODS: 184 SCLC patients’ primary tumour samples were analyzed for ERCCI, BRCA1, ATP7B, PKM2 TOPOI, TOPOIIA, TOPOIIB and C-MYC mRNA express...

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Detalhes bibliográficos
Main Authors: Karachaliou, Niki, Papadaki, Chara, Lagoudaki, Eleni, Trypaki, Maria, Sfakianaki, Maria, Koutsopoulos, Anastasios, Mavroudis, Dimitris, Stathopoulos, Efstathios, Georgoulias, Vassilis, Souglakos, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772910/
https://ncbi.nlm.nih.gov/pubmed/24058603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074611
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