The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer

BACKGROUND: The hypoxia marker pimonidazole is a candidate biomarker of cancer aggressiveness. We investigated the transcriptional programme associated with pimonidazole staining in prostate cancer. METHODS: Index tumour biopsies were taken by image guidance from an investigation cohort of 52 patien...

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Vydáno v:Br J Cancer
Hlavní autoři: Ragnum, H B, Vlatkovic, L, Lie, A K, Axcrona, K, Julin, C H, Frikstad, K M, Hole, K H, Seierstad, T, Lyng, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453458/
https://ncbi.nlm.nih.gov/pubmed/25461803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.604
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